An NS5A single optimized method to determine genotype, subtype and resistance profiles of Hepatitis C strains

The objective was to develop a method of HCV genome sequencing that allowed simultaneous genotyping and NS5A inhibitor resistance profiling. In order to validate the use of a unique RT-PCR for genotypes 1–5, 142 plasma samples from patients infected with HCV were analysed. The NS4B-NS5A partial regi...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Andre-Garnier, Elisabeth, Besse, Bernard, Rodallec, Audrey, Ribeyrol, Olivier, Ferre, Virginie, Luco, Caroline, Le Guen, Laura, Bourgeois, Nathalie, Gournay, Jérôme, Billaud, Eric, Raffi, François, Coste-Burel, Marianne, Imbert-Marcille, Berthe-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519038/
https://ncbi.nlm.nih.gov/pubmed/28727784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179562
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