Large-Scale ATP-Independent Nucleosome Unfolding by a Histone Chaperone

DNA accessibility to regulatory proteins is significantly affected by nucleosome structure and dynamics. FACT (facilitates chromatin transcription) increases the accessibility of nucleosomal DNA but the mechanism and extent of this nucleosome reorganization are unknown. We report here the effects of...

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Udgivet i:Nat Struct Mol Biol
Main Authors: Valieva, Maria E., Armeev, Grigoriy A., Kudryashova, Kseniya S., Gerasimova, Nadezhda S., Shaytan, Alexey K., Kulaeva, Olga I., McCullough, Laura L., Formosa, Tim, Georgiev, Pavel G., Kirpichnikov, Mikhail P., Studitsky, Vasily M., Feofanov, Alexey V.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518926/
https://ncbi.nlm.nih.gov/pubmed/27820806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3321
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