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Selective binding of ligands to beta 1, beta 2 or chimeric beta 1/beta 2-adrenergic receptors involves multiple subsites.

The molecular basis of ligand binding selectivity to beta-adrenergic receptor subtypes was investigated by designing chimeric beta 1/beta 2-adrenergic receptors. These molecules consisted of a set of reciprocal constructions, obtained by the exchange between the wild-type receptor genes of one to th...

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Bibliografiska uppgifter
Huvudupphovsmän: Marullo, S, Emorine, L J, Strosberg, A D, Delavier-Klutchko, C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC551837/
https://ncbi.nlm.nih.gov/pubmed/1970295
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