Computational design of a symmetrical β-trefoil lectin with cancer cell binding activity

Computational protein design has advanced very rapidly over the last decade, but there remain few examples of artificial proteins with direct medical applications. This study describes a new artificial β-trefoil lectin that recognises Burkitt’s lymphoma cells, and which was designed with the intenti...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Terada, Daiki, Voet, Arnout R. D., Noguchi, Hiroki, Kamata, Kenichi, Ohki, Mio, Addy, Christine, Fujii, Yuki, Yamamoto, Daiki, Ozeki, Yasuhiro, Tame, Jeremy R. H., Zhang, Kam Y. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517649/
https://ncbi.nlm.nih.gov/pubmed/28724971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06332-7
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