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CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production

Eosinophils and their associated cytokines IL-4 and IL-5 are emerging as central orchestrators of the immune-metabolic axis. Herein, we demonstrate that cross-talk between the Ig-superfamily receptor CD300f and IL-5 is a key checkpoint that modifies the ability of eosinophils to regulate metabolic o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rozenberg, Perri, Reichman, Hadar, Zab-Bar, Israel, Itan, Michal, Pasmanik-Chor, Metsada, Bouffi, Carine, Qimron, Udi, Bachelet, Ido, Fulkerson, Patricia C., Rothenberg, Marc E., Munitz, Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517555/
https://ncbi.nlm.nih.gov/pubmed/28725048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06397-4
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