CD300f associates with IL-4 receptor α and amplifies IL-4–induced immune cell responses

IL-4 receptor (R) α, the common receptor chain for IL-4 and IL-13, is a critical component in IL-4– and IL-13–mediated signaling and subsequent effector functions such as those observed in type 2 inflammatory responses. Nonetheless, the existence of intrinsic pathways capable of amplifying IL-4Rα–in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Moshkovits, Itay, Karo-Atar, Danielle, Itan, Michal, Reichman, Hadar, Rozenberg, Perri, Morgenstern-Ben-Baruch, Netali, Shik, Dana, Ejarque-Ortiz, Aroa, Hershko, Alon Y., Tian, Linjie, Coligan, John E., Sayós, Joan, Munitz, Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507247/
https://ncbi.nlm.nih.gov/pubmed/26124135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507625112
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