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Modulation of RNA primer formation by Mn(II)-substituted T7 DNA primase
Lagging strand DNA synthesis by DNA polymerase requires RNA primers produced by DNA primase. The N-terminal primase domain of the gene 4 protein of phage T7 comprises a zinc-binding domain that recognizes a specific DNA sequence and an RNA polymerase domain that catalyzes RNA polymerization. Based o...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517523/ https://ncbi.nlm.nih.gov/pubmed/28724886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05534-3 |
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