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IL-1β activation of non-muscle myosin light chain kinase mediates β-catenin driven downregulation of claudin-3 and barrier dysfunction in Caco2 cells
BACKGROUND: IL-1β is a cytokine involved in mediating epithelial barrier dysfunction in the gut. It is known that IL-1β mediates activation of non-muscle myosin light chain kinase in epithelial cells, but the precise mechanism by which epithelial barrier dysfunction is induced by IL-1β is not unders...
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| Veröffentlicht in: | Dig Dis Sci |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517031/ https://ncbi.nlm.nih.gov/pubmed/27074920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-016-4145-y |
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