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High affinity anti-TIM-3 and anti-KIR monoclonal antibodies cloned from healthy human individuals
We report here the cloning of native high affinity anti-TIM-3 and anti-KIR IgG monoclonal antibodies (mAbs) from peripheral blood mononuclear cells (PBMC) of healthy human donors. The cells that express these mAbs are rare, present at a frequency of less than one per 10(5) memory B-cells. Using our...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517007/ https://ncbi.nlm.nih.gov/pubmed/28723950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181464 |
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