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A High-Affinity Native Human Antibody Disrupts Biofilm from Staphylococcus aureus Bacteria and Potentiates Antibiotic Efficacy in a Mouse Implant Infection Model
Many serious bacterial infections are difficult to treat due to biofilm formation, which provides physical protection and induces a sessile phenotype refractory to antibiotic treatment compared to the planktonic state. A key structural component of biofilm is extracellular DNA, which is held in plac...
Gorde:
Argitaratua izan da: | Antimicrob Agents Chemother |
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Egile Nagusiak: | , , , , , , , , , , , , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Microbiology
2016
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4808150/ https://ncbi.nlm.nih.gov/pubmed/26833157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02588-15 |
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