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A High-Affinity Native Human Antibody Disrupts Biofilm from Staphylococcus aureus Bacteria and Potentiates Antibiotic Efficacy in a Mouse Implant Infection Model
Many serious bacterial infections are difficult to treat due to biofilm formation, which provides physical protection and induces a sessile phenotype refractory to antibiotic treatment compared to the planktonic state. A key structural component of biofilm is extracellular DNA, which is held in plac...
Zapisane w:
Wydane w: | Antimicrob Agents Chemother |
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Główni autorzy: | , , , , , , , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
American Society for Microbiology
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4808150/ https://ncbi.nlm.nih.gov/pubmed/26833157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02588-15 |
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