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Arginine-lysine Positional Swap of the LL-37 Peptides Reveals Evolutional Advantages of the Native Sequence and Leads to Bacterial Probes

Antimicrobial peptides are essential components of the innate immune system of multicellular organisms. Although cationic and hydrophobic amino acids are known determinants of these amphipathic molecules for bacterial killing, it is not clear how lysine-arginine (K-R) positional swaps influence pept...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Wang, Xiuqing, Junior, José Carlos Bozelli, Mishra, Biswajit, Lushnikova, Tamara, Epand, Richard M., Wang, Guangshun
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516960/
https://ncbi.nlm.nih.gov/pubmed/28450045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2017.04.018
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