Nutlin-3 Treatment Spares Cisplatin-Induced Inhibition of Bone Healing While Maintaining Osteosarcoma Toxicity

The majority of Osteosarcoma (OS) patients are treated with a combination of chemotherapy, resection, and limb salvage protocols. These protocols include distraction osteogenesis (DO), which is characterized by direct new bone formation. Cisplatin (CDP) is extensively used for OS chemotherapy and re...

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Détails bibliographiques
Publié dans:J Orthop Res
Auteurs principaux: Stine, Kimo C., Wahl, Elizabeth C., Liu, Lichu, Skinner, Robert A., VanderSchilden, Jaclyn, Bunn, Robert C., Montgomery, Corey O., Aronson, James, Becton, David L., Nicholas, Richard W., Swearingen, Christopher J., Suva, Larry J., Lumpkin, Charles K.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516939/
https://ncbi.nlm.nih.gov/pubmed/26867804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23192
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