Nutlin-3 Treatment Spares Cisplatin-Induced Inhibition of Bone Healing While Maintaining Osteosarcoma Toxicity

The majority of Osteosarcoma (OS) patients are treated with a combination of chemotherapy, resection, and limb salvage protocols. These protocols include distraction osteogenesis (DO), which is characterized by direct new bone formation. Cisplatin (CDP) is extensively used for OS chemotherapy and re...

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Udgivet i:J Orthop Res
Main Authors: Stine, Kimo C., Wahl, Elizabeth C., Liu, Lichu, Skinner, Robert A., VanderSchilden, Jaclyn, Bunn, Robert C., Montgomery, Corey O., Aronson, James, Becton, David L., Nicholas, Richard W., Swearingen, Christopher J., Suva, Larry J., Lumpkin, Charles K.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516939/
https://ncbi.nlm.nih.gov/pubmed/26867804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23192
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