Chronic Ethanol Exposure Inhibits Distraction Osteogenesis in a Mouse Model: Role of the TNF Signaling Axis

Tumor necrosis factor-α (TNF-α) is an inflammatory cytokine that modulates osteoblastogenesis. In addition, the demonstrated inhibitory effects of chronic ethanol exposure on direct bone formation in rats is hypothetically mediated by TNF-α signaling. The effects in mice are unreported. Therefore, w...

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Main Authors: Wahl, Elizabeth C., Aronson, James, Liu, Lichu, Liu, Zhendong, Perrien, Daniel S., Skinner, Robert A., Badger, Thomas M., Ronis, Martin JJ, Lumpkin, Charles K.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892174/
https://ncbi.nlm.nih.gov/pubmed/17391719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2007.02.011
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