[(18)F]Fluoroethyl Triazole Substituted PSMA Inhibitor Exhibiting Rapid Normal Organ Clearance

Prostate-specific membrane antigen (PSMA) is overexpressed in the epithelium of prostate cancer and nonprostate solid tumor neovasculature. PSMA is increasingly utilized as a target for cancer imaging and therapy. Here, we report the synthesis and in vivo biodistribution of a low-molecular-weight PS...

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Bibliografske podrobnosti
izdano v:Bioconjug Chem
Main Authors: Chen, Ying, Lisok, Ala, Chatterjee, Samit, Wharram, Bryan, Pullambhatla, Mrudula, Wang, Yuchuan, Sgouros, George, Mease, Ronnie C., Pomper, Martin G.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516890/
https://ncbi.nlm.nih.gov/pubmed/27270097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.6b00195
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