[(18)F]Fluorobenzoyllysinepentanedioic Acid Carbamates: New Scaffolds for Positron Emission Tomography (PET) Imaging of Prostate-Specific Membrane Antigen (PSMA)

Radiolabeled urea-based low-molecular weight inhibitors of the prostate-specific membrane antigen (PSMA) are under intense investigation as imaging and therapeutic agents for prostate and other cancers. In an effort to provide agents with less nontarget organ uptake than the ureas, we synthesized fo...

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Veröffentlicht in:J Med Chem
Hauptverfasser: Yang, Xing, Mease, Ronnie C., Pullambhatla, Mrudula, Lisok, Ala, Chen, Ying, Foss, Catherine A., Wang, Yuchuan, Shallal, Hassan, Edelman, Hannah, Hoye, Adam T., Attardo, Giorgio, Nimmagadda, Sridhar, Pomper, Martin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856055/
https://ncbi.nlm.nih.gov/pubmed/26629713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01268
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