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Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site.

Intracellular proteolytic processing of precursor polypeptides is an essential step in the maturation of many proteins, including plasma proteins, hormones, neuropeptides, and growth factors. Most frequently, propeptide cleavage occurs after paired basic amino acid residues. To date, no mammalian pr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Wise, R J, Barr, P J, Wong, P A, Kiefer, M C, Brake, A J, Kaufman, R J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2251280/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9378
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