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Determination of the optimal sample size for a clinical trial accounting for the population size

The problem of choosing a sample size for a clinical trial is a very common one. In some settings, such as rare diseases or other small populations, the large sample sizes usually associated with the standard frequentist approach may be infeasible, suggesting that the sample size chosen should refle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biom J
Hauptverfasser: Stallard, Nigel, Miller, Frank, Day, Simon, Hee, Siew Wan, Madan, Jason, Zohar, Sarah, Posch, Martin
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516263/
https://ncbi.nlm.nih.gov/pubmed/27184938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bimj.201500228
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