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Estimation after blinded sample size reassessment

Blinded sample size reassessment is a popular means to control the power in clinical trials if no reliable information on nuisance parameters is available in the planning phase. We investigate how sample size reassessment based on blinded interim data affects the properties of point estimates and co...

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Bibliografiske detaljer
Udgivet i:Stat Methods Med Res
Main Authors: Posch, Martin, Klinglmueller, Florian, König, Franz, Miller, Frank
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047306/
https://ncbi.nlm.nih.gov/pubmed/27697838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0962280216670424
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