Mitochondrial Cochaperone Mge1 Is Involved in Regulating Susceptibility to Fluconazole in Saccharomyces cerevisiae and Candida Species

MGE1 encodes a yeast chaperone involved in Fe-S cluster metabolism and protein import into the mitochondria. In this study, we identified MGE1 as a multicopy suppressor of susceptibility to the antifungal fluconazole in the model yeast Saccharomyces cerevisiae. We demonstrate that this phenomenon is...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Demuyser, Liesbeth, Swinnen, Erwin, Fiori, Alessandro, Herrera-Malaver, Beatriz, Verstrepen, Kevin, Van Dijck, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5516249/
https://ncbi.nlm.nih.gov/pubmed/28720726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00201-17
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