Fluconazole impacts the extracellular matrix of fluconazole-susceptible and -resistant Candida albicans and Candida glabrata biofilms

Background: Fluconazole (FLZ) is a drug commonly used for the treatment of Candida infections. However, β-glucans in the extracellular matrices (ECMs) hinder FLZ penetration into Candida biofilms, while extracellular DNA (eDNA) contributes to the biofilm architecture and resistance. Methods: This st...

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Publicado en:J Oral Microbiol
Main Authors: Panariello, Beatriz Helena Dias, Klein, Marlise I., Mima, Ewerton Garcia De Oliveira, Pavarina, Ana Cláudia
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2018
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5990947/
https://ncbi.nlm.nih.gov/pubmed/29887974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20002297.2018.1476644
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