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Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is Mediated by Interference with Iron Homeostasis
Doxycycline was found to act synergistically with the antifungal fluconazole against Candida albicans. Combination with doxycycline converts fluconazole from fungistatic to fungicidal, prevents the onset of drug resistance, and is also effective against a clinical isolate characterized by elevated r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3393430/ https://ncbi.nlm.nih.gov/pubmed/22564841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06017-11 |
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