MICE LACKING LIVER-SPECIFIC β-CATENIN DEVELOP STEATOHEPATITIS AND FIBROSIS AFTER IRON OVERLOAD

BACKGROUND & AIMS: Iron overload disorders such as hereditary hemochromatosis and iron-loading anemias are a common cause of morbidity from liver diseases and increase risk of hepatic fibrosis and hepatocellular carcinoma (HCC). Once iron-induced damage occurs, treatment options are limited part...

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Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Preziosi, Morgan E., Singh, Sucha, Valore, Erika V., Jung, Chun-Ling, Popovic, Branimir, Poddar, Minakshi, Nagarajan, Shanmugam, Ganz, Tomas, Monga, Satdarshan P
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515705/
https://ncbi.nlm.nih.gov/pubmed/28341391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2017.03.012
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