Metformin effects on head and neck squamous carcinoma microenvironment: Window of opportunity trial

OBJECTIVE: The tumor microenvironment frequently displays abnormal cellular metabolism, which contributes to aggressive behavior. Metformin inhibits mitochondrial oxidative phosphorylation, altering metabolism. Though the mechanism is unclear, epidemiologic studies show an association between metfor...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Laryngoscope
मुख्य लेखकों: Curry, Joseph, Johnson, Jennifer, Tassone, Patrick, Vidal, Marina Domingo, Menezes, Diana Whitaker, Sprandio, John, Mollaee, Mehri, Cotzia, Paolo, Birbe, Ruth, Lin, Zhao, Gill, Kurren, Duddy, Elizabeth, Zhan, Tingting, Leiby, Benjamin, Reyzer, Michelle, Cognetti, David, Luginbuhl, Adam, Tuluc, Madalina, Martinez‐Outschoorn, Ubaldo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2017
विषय:
Head and Neck
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515672/
https://ncbi.nlm.nih.gov/pubmed/28185288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.26489
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