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Immune response to JC virus T antigen in patients with and without colorectal neoplasia

JC virus (JCV) is a polyomavirus that infects approximately 75% of the population and encodes a T antigen (T-Ag) gene, which is oncogenic and inactivates the p53 and pRb/p107/p130 protein families. Previous work in our lab has identified the presence of T-Ag in colorectal neoplasms. While JCV remain...

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Detalhes bibliográficos
Publicado no:Gut Microbes
Main Authors: Butcher, Lindsay D, Garcia, Melissa, Arnold, Mildred, Ueno, Hideki, Goel, Ajay, Boland, C Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515464/
https://ncbi.nlm.nih.gov/pubmed/25007286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.29573
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