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JC Virus T-Antigen Expression in Anal Carcinoma

BACKGROUND & AIMS: Anal carcinoma is thought driven by HPV infection through interrupting function of cell regulatory proteins such as p53 and pRb. JCV expresses a T-antigen (T-Ag) that causes malignant transformation through development of aneuploidy and interaction with some of the same regula...

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Main Authors: Ramamoorthy, Sonia, Deveraj, Bikash, Miyai, Katsumi, Luo, Linda, Liu, Yu-Tsueng, Boland, C. Richard, Goel, Ajay, Carethers, John M.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060305/
https://ncbi.nlm.nih.gov/pubmed/24048785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25793
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