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JC Virus Mediates Invasion and Migration in Colorectal Metastasis

INTRODUCTION: JC Virus (JCV), a human polyomavirus, is frequently present in colorectal cancers (CRCs). JCV large T-Ag (T-Ag) expressed in approximately half of all CRC's, however, its functional role in CRC is poorly understood. We hypothesized that JCV T-Ag may mediate metastasis in CRC cells...

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Detalhes bibliográficos
Main Authors: Link, Alexander, Shin, Sung Kwan, Nagasaka, Takeshi, Balaguer, Francesc, Koi, Minoru, Jung, Barbara, Boland, C. Richard, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781631/
https://ncbi.nlm.nih.gov/pubmed/19997600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008146
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