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3D single-molecule tracking enables direct hybridization kinetics measurement in solution
Single-molecule measurements of DNA hybridization kinetics are mostly performed on a surface or inside a trap. Here we demonstrate a time-resolved, 3D single-molecule tracking (3D-SMT) method that allows us to follow a freely diffusing ssDNA molecule in solution for hundreds of milliseconds or even...
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| Udgivet i: | Nanoscale |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5515391/ https://ncbi.nlm.nih.gov/pubmed/28422238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7nr01369h |
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