Measuring DNA Hybridization Kinetics in Live Cells Using a Time-Resolved 3D Single-Molecule Tracking Method

Single-molecule detection enables direct characterization of annealing/melting kinetics of nucleic acids without the need for synchronization of molecular states, but the current experiments are not carried out in a native cellular context. Here we describe an integrated 3D single-molecule tracking...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Chen, Yuan-I, Chang, Yin-Jui, Nguyen, Trung Duc, Liu, Cong, Phillion, Stephanie, Kuo, Yu-An, Vu, Huong T., Liu, Angela, Liu, Yen-Liang, Hong, Soonwoo, Ren, Pengyu, Yankeelov, Thomas E., Yeh, Hsin-Chih
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179573/
https://ncbi.nlm.nih.gov/pubmed/31509386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b08036
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