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LNA Thymidine Monomer Enables Differentiation of the Four Single-Nucleotide Variants by Melting Temperature
High-resolution melting (HRM) analysis of DNA is a closed-tube single-nucleotide polymorphism (SNP) detection method that has shown many advantages in point-of-care diagnostics and personalized medicine. While recently developed melting probes have demonstrated significantly improved discrimination...
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| Publicado no: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5850941/ https://ncbi.nlm.nih.gov/pubmed/28463488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b03395 |
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