Prevalence and predictors of androgen receptor and programmed death-ligand 1 in BRCA1-associated and sporadic triple-negative breast cancer

BACKGROUND: Triple-negative breast cancers comprise 15% of breast cancers and are more common in women with BRCA1 mutations. Although most have basal gene expression signatures, others resemble luminal tumors with expression of androgen receptor-related genes and some express the immunoinhibitory pr...

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Vydáno v:NPJ Breast Cancer
Hlavní autoři: Tung, Nadine, Garber, Judy E, Hacker, Michele R, Torous, Vanda, Freeman, Gordon J, Poles, Emily, Rodig, Scott, Alexander, Brian, Lee, Larissa, Collins, Laura C, Schnitt, Stuart J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5515333/
https://ncbi.nlm.nih.gov/pubmed/28721372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjbcancer.2016.2
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