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cAMP-mediated Inhibition of DNA Replication and S Phase Progression: Involvement of Rb, p21(Cip1), and PCNA
cAMP exerts an antiproliferative effect on a number of cell types including lymphocytes. This effect of cAMP is proposed to be mediated by its ability to inhibit G1/S transition. In this report, we provide evidence for a new mechanism whereby cAMP might inhibit cellular proliferation. We show that e...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC551513/ https://ncbi.nlm.nih.gov/pubmed/15647383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-06-0501 |
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