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Inhibition of DNA synthesis by RB: effects on G(1)/S transition and S-phase progression
The retinoblastoma tumor suppressor protein, RB, is a negative regulator of cell proliferation. Growth inhibitory activity of RB is attenuated by phosphorylation. Mutation of a combination of phosphorylation sites leads to a constitutively active RB. In Rat-1 cells, the phosphorylation-site-mutated...
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| 出版年: | Genes Dev |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317048/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9694794/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.15.2278 |
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