Anti-tumor activity of an immunotoxin (TGFα-PE38) delivered by attenuated Salmonella typhimurium

The anticancer strategy underlying the use of immunotoxins is as follows: the cancer-binding domain delivers the toxin to a cancer cell, after which the toxin enters and kills the cell. TGFα-PE38 is an immunotoxin comprising transforming growth factor alpha (TGFα), a natural ligand of epidermal grow...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Lim, Daejin, Kim, Kwang Soo, Kim, Hyunju, Ko, Kyong-Cheol, Song, Jae Jun, Choi, Jong Hyun, Shin, Minsang, Min, Jung-joon, Jeong, Jae-Ho, Choy, Hyon E.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514929/
https://ncbi.nlm.nih.gov/pubmed/28473665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17197
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