L-Asparaginase delivered by Salmonella typhimurium suppresses solid tumors

Bacteria can be engineered to deliver anticancer proteins to tumors via a controlled expression system that maximizes the concentration of the therapeutic agent in the tumor. L-asparaginase (L-ASNase), which primarily converts asparagine to aspartate, is an anticancer protein used to treat acute lym...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Kim, Kwangsoo, Jeong, Jae Ho, Lim, Daejin, Hong, Yeongjin, Lim, Hyung-Ju, Kim, Geun-Joong, Shin, So-ra, Lee, Je-Jung, Yun, Misun, Harris, Robert A, Min, Jung-Joon, Choy, Hyon E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845971/
https://ncbi.nlm.nih.gov/pubmed/27119104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2015.7
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