Folic acid phenotype (FAP) is a superior biomarker predicting response to pemetrexed-based chemotherapy in malignant pleural mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare tumor linked to a dismal prognosis. Even the most effective chemotherapeutical regime of pemetrexed combined with cisplatin leads to a remission-rate of only about 40%. The reasons for the rather poor efficacy remain largely unknown. RESULTS...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Mairinger, Fabian Dominik, Vollbrecht, Claudia, Flom, Elena, Christoph, Daniel Christian, Schmid, Kurt-Werner, Kollmeier, Jens, Popper, Helmut Hans, Mairinger, Thomas, Henry Walter, Robert Fred
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514925/
https://ncbi.nlm.nih.gov/pubmed/28415584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16398
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