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Screening of Pleural Mesotheliomas for DNA-damage Repair Players by Digital Gene Expression Analysis Can Enhance Clinical Management of Patients Receiving Platin-Based Chemotherapy

Background: Malignant pleural mesothelioma (MPM) is a rare, predominantly asbestos-related and biologically highly aggressive tumour leading to a dismal prognosis. Multimodality therapy consisting of platinum-based chemotherapy is the treatment of choice. The reasons for the rather poor efficacy of...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Walter, Robert Fred Henry, Vollbrecht, Claudia, Werner, Robert, Mairinger, Thomas, Schmeller, Jan, Flom, Elena, Wohlschlaeger, Jeremias, Barbetakis, Nikolaos, Paliouras, Dimitrios, Chatzinikolaou, Fotios, Adamidis, Vasilis, Tsakiridis, Kosmas, Zarogoulidis, Paul, Trakada, Georgia, Christoph, Daniel Christian, Schmid, Kurt Werner, Mairinger, Fabian Dominik
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039377/
https://ncbi.nlm.nih.gov/pubmed/27698933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.16390
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