Folic-acid metabolism and DNA-repair phenotypes differ between neuroendocrine lung tumors and associate with aggressive subtypes, therapy resistance and outcome

PURPOSE: 25% of all lung cancer cases are neuroendocrine (NELC) including typical (TC) and atypical carcinoid (AC), large-cell neuroendocrine (LCNEC) and small cell lung cancer (SCLC). Prognostic and predictive biomarkers are lacking. EXPERIMENTAL DESIGN: Sixty patients were used for nCounter mRNA e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Henry Walter, Robert Fred, Mairinger, Fabian Dominik, Werner, Robert, Vollbrecht, Claudia, Hager, Thomas, Schmid, Kurt Werner, Wohlschlaeger, Jeremias, Christoph, Daniel Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991445/
https://ncbi.nlm.nih.gov/pubmed/27064343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7737
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