Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity

Autoimmune diseases such as systemic lupus erythematosus (SLE) are associated with increased cardiovascular disease and reduced plasma high-density lipoproteins (HDL) levels. HDL mediates cholesterol efflux from immune cells via the ATP Binding Cassette Transporters A1 and G1 (ABCA1/G1). The signifi...

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Udgivet i:Cell Metab
Main Authors: Westerterp, Marit, Gautier, Emmanuel L., Ganda, Anjali, Molusky, Matthew M., Wang, Wei, Fotakis, Panagiotis, Wang, Nan, Randolph, Gwendalyn J., D’Agati, Vivette D., Yvan-Charvet, Laurent, Tall, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514787/
https://ncbi.nlm.nih.gov/pubmed/28479366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.04.005
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