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DNA–PK facilitates piggyBac transposition by promoting paired-end complex formation

The involvement of host factors is critical to our understanding of underlying mechanisms of transposition and the applications of transposon-based technologies. Modified piggyBac (PB) is one of the most potent transposon systems in mammals. However, varying transposition efficiencies of PB among di...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jin, Yan, Chen, Yaohui, Zhao, Shimin, Guan, Kun-Liang, Zhuang, Yuan, Zhou, Wenhao, Wu, Xiaohui, Xu, Tian
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514698/
https://ncbi.nlm.nih.gov/pubmed/28645898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612980114
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