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KEAP1-NRF2 Signaling and Autophagy in Protection against Oxidative and Reductive Proteotoxicity

Maintaining cellular redox status to allow cell signaling to occur requires modulation of both the controlled production of oxidants and the thiol reducing networks to allow specific regulatory post-translational modification of protein thiols. The oxidative stress hypothesis captures the concept th...

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Bibliographic Details
Published in:Biochem J
Main Authors: Dodson, Matthew, Redmann, Matthew, Rajasekaran, Namakkal S., Darley-Usmar, Victor, Zhang, Jianhua
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514546/
https://ncbi.nlm.nih.gov/pubmed/26205490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150568
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