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An efficient algorithm for improving structure-based prediction of transcription factor binding sites

BACKGROUND: Gene expression is regulated by transcription factors binding to specific target DNA sites. Understanding how and where transcription factors bind at genome scale represents an essential step toward our understanding of gene regulation networks. Previously we developed a structure-based...

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Pubblicato in:BMC Bioinformatics
Autori principali: Farrel, Alvin, Guo, Jun-tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514533/
https://ncbi.nlm.nih.gov/pubmed/28715997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1755-0
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