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Structure-based prediction of transcription factor binding specificity using an integrative energy function

Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regulation networks. In this article, we present a struct...

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Dettagli Bibliografici
Pubblicato in:Bioinformatics
Autori principali: Farrel, Alvin, Murphy, Jonathan, Guo, Jun-tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908348/
https://ncbi.nlm.nih.gov/pubmed/27307632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw264
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