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Structure-based prediction of transcription factor binding specificity using an integrative energy function

Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regulation networks. In this article, we present a struct...

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Publicat a:Bioinformatics
Autors principals: Farrel, Alvin, Murphy, Jonathan, Guo, Jun-tao
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908348/
https://ncbi.nlm.nih.gov/pubmed/27307632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw264
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