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Structure-based prediction of transcription factor binding specificity using an integrative energy function

Transcription factors (TFs) regulate gene expression through binding to specific target DNA sites. Accurate annotation of transcription factor binding sites (TFBSs) at genome scale represents an essential step toward our understanding of gene regulation networks. In this article, we present a struct...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Farrel, Alvin, Murphy, Jonathan, Guo, Jun-tao
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908348/
https://ncbi.nlm.nih.gov/pubmed/27307632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw264
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