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An efficient algorithm for improving structure-based prediction of transcription factor binding sites

BACKGROUND: Gene expression is regulated by transcription factors binding to specific target DNA sites. Understanding how and where transcription factors bind at genome scale represents an essential step toward our understanding of gene regulation networks. Previously we developed a structure-based...

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Publicat a:BMC Bioinformatics
Autors principals: Farrel, Alvin, Guo, Jun-tao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514533/
https://ncbi.nlm.nih.gov/pubmed/28715997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1755-0
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