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Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells
The R5 subfamily of receptor-type protein tyrosine phosphatases (RPTPs) comprises PTPRZ and PTPRG. A recent study on primary human glioblastomas suggested a close association between PTPRZ1 (human PTPRZ) expression and cancer stemness. However, the functional roles of PTPRZ activity in glioma stem c...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514153/ https://ncbi.nlm.nih.gov/pubmed/28717188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05931-8 |
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