Gα(s) signalling of the CB(1) receptor and the influence of receptor number

BACKGROUND AND PURPOSE: CB(1) receptor signalling is canonically mediated through inhibitory Gα(i) proteins, but occurs through other G proteins under some circumstances, Gα(s) being the most characterized secondary pathway. Determinants of this signalling switch identified to date include Gα(i) blo...

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Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Finlay, David B, Cawston, Erin E, Grimsey, Natasha L, Hunter, Morag R, Korde, Anisha, Vemuri, V Kiran, Makriyannis, Alexandros, Glass, Michelle
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513864/
https://ncbi.nlm.nih.gov/pubmed/28516479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13866
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