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Identification of N‐arachidonoyl dopamine as a highly biased ligand at cannabinoid CB(1) receptors

BACKGROUND AND PURPOSE: N‐arachidonyl dopamine (NADA) has been identified as a putative endocannabinoid, but there is little information about which signalling pathways it activates. The purpose of this study was to identify the signalling pathways activated by NADA in vitro. EXPERIMENTAL APPROACH:...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Redmond, William J., Cawston, Erin E., Grimsey, Natasha L., Stuart, Jordyn, Edington, Amelia R., Glass, Michelle, Connor, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813372/
https://ncbi.nlm.nih.gov/pubmed/26398720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13341
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