Identification of N‐arachidonoyl dopamine as a highly biased ligand at cannabinoid CB(1) receptors

BACKGROUND AND PURPOSE: N‐arachidonyl dopamine (NADA) has been identified as a putative endocannabinoid, but there is little information about which signalling pathways it activates. The purpose of this study was to identify the signalling pathways activated by NADA in vitro. EXPERIMENTAL APPROACH:...

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Udgivet i:Br J Pharmacol
Main Authors: Redmond, William J., Cawston, Erin E., Grimsey, Natasha L., Stuart, Jordyn, Edington, Amelia R., Glass, Michelle, Connor, Mark
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813372/
https://ncbi.nlm.nih.gov/pubmed/26398720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13341
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