SB 9200, a novel agonist of innate immunity, shows potent antiviral activity against resistant HCV variants

SB 9200 is a novel, first-in-class oral modulator of innate immunity that is believed to act via the activation of the RIG-I and NOD2 pathways. SB 9200 has broad-spectrum antiviral activity against RNA viruses including hepatitis C virus (HCV), norovirus, respiratory syncytial virus and influenza an...

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Vydáno v:J Med Virol
Hlavní autoři: Jones, Meleri, Cunningham, Morven E., Wing, Peter, DeSilva, Sampath, Challa, Rupa, Sheri, Anjaneyulu, Padmanabhan, Seetharamaiyer, Iyer, Radhakrishnan P., Korba, Brent E., Afdhal, Nezam, Foster, Graham R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513743/
https://ncbi.nlm.nih.gov/pubmed/28303593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.24809
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