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Insulin-Like Growth Factor-I-Stimulated Akt Phosphorylation and Oligodendrocyte Progenitor Cell Survival Require Cholesterol-Enriched Membranes

Previously we showed that insulin-like growth factor-I (IGF-I) promotes sustained phosphorylation of Akt in oligodendrocyte progenitor cells (OPCs) and that Akt phosphorylation is required for survival of these cells. The direct mechanisms, however, by which IGF-I promotes Akt phosphorylation are cu...

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Detalhes bibliográficos
Publicado no:J Neurosci Res
Main Authors: Romanelli, Robert J., Mahajan, Kedar R., Fulmer, Clifton G., Wood, Teresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513484/
https://ncbi.nlm.nih.gov/pubmed/19382214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22099
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